![N-[6-(Biotinamido)hexyl]-3-(2-pyridyldithio)-propionamide; Biotin-HPDP Structure, CAS # 129179-83-5](http://proteochem.com/images/structure_images/Biotin-HPDP-structure.gif)
N-[6-(Biotinamido)hexyl]-3-(2-pyridyldithio)-propionamide (Biotin-HPDP) is a sulfhydryl reactive biotinylation reagent with a long chain, cleavable spacer arm. Biotin-HPDP biotinylation occurs between pH 6-9 through its pyridyldithiol group reacting with sulfhydryls to form a stable disulfide bond. The 29.2 angstrom spacer arm prevents steric hindrance and may also be cleaved at the disulfide bond using TCEP-HCl, DTT or ß-Mercaptoethanol.Biotin-HPDP must be dissolved in an organic solvent, such as DMSO or DMF, then added to an aqueous biotinylation reaction. The resulting biotinylated protein can then be detected when used in conjunction with streptavidin or Immobilized Streptavidin.
Spacer Length: 29.2 ÅMolecular Weight: 539.78CAS Number: 129179-83-5Alternative Names: Biotin HPDP; Pyridyldithiol-biotin; Pyridyldisulfide-biotinSpecial bulk pricing is available on bulk quantities of Biotin-HPDP biotinylation reagent for your large volume manufacturing application.ProteoChem是一家生物技术和化学试剂制造公司，专门从事蛋白质生物化学和有机合成。ProteoChem生产用于NMR，质谱，蛋白质交联剂和用于蛋白质检测和蛋白质修饰的新型蛋白质组学试剂的分析标准品，这些试剂用于质谱，药物开发，诊断和蛋白质生物学中。
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