Sulfo-SMCCcrosslinker(Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate)isawatersoluble,heterobifunctionalcrosslinker(SMCCisthewaterinsolubleproteincrosslinkinganalogofSulfo-SMCCcrosslinker).Assuch,thenon-membranepiercingSulfo-SMCCproteincrosslinkingreagentcanconjugateextracellularproteins.
Sulfo-SMCCcrosslinkerhasan8.3angstrom,non-cleavablespacerarm.Sulfo-SMCCconjugationoccursviaamaleimidegroupwhichreactswithsulfhydryls(thiols,-SH),whileitsSulfo-NHSesterisreactivetowardprimaryamines(asfoundinLysineandtheproteinorpeptideN-terminus).Sulfo-SMCCcrosslinkingreagentisroutinelyusedtopreparehapten-carrierprotein,polymers,andantibody-enzymeconjugates,suchasHRPconjugation.
SATAProteinModifiercanbeusedtoaddsulfhydrylgroups(thiols,-SH)toproteinsorpeptidespriortoSulfo-SMCCcrosslinking.
Clickherefor:Sulfo-SMCCProtocol&ProductInformationSheet
MolecularWeight:436.37
SpacerLength:8.3Å
CASNumber:92921-24-9
ChemicalFormula:C
16H
17N
2NaO
9S
AlternativeNames:4-(N-Maleimidomethyl)cyclohexane-1-carboxylicacid3-sulfo-N-hydroxysuccinimideester;WaterSolubleSMCC;Sulfo-SMCCX-linker;SSMCC;S-SMCC;Sulfosuccinimidyl-4-N-maleimidomethyl-cyclohexane-1-carboxylate;SulfoSMCCCASNumber92921-24-9
SpecialbulkpricingisavailableonbulkquantitiesofSulfo-SMCCcrosslinker(CAS#92921-24-9)foryourlargevolumemanufacturingapplication.