DSTcrosslinker(Disuccinimidyltartrate)isahomobifunctional,cleavablecrosslinkingreagentbyoxidizingreagents.DSTproteincrosslinkerhasacis-diolthatiscleavedwith15mMSodiummeta-Periodate.TheDSTcrosslinkingreagentcontainstwoN-hydroxysuccimide(NHS)estergroupsandisreactivetowardprimaryamines(aminogroups),suchasfoundonlysineandtheN-terminus.DSTcrosslinkerisanexcellentchoiceforapplicationsinwhichcrosslinkcleav
ABIlityisdesiredwithoutdisturbingproteindisulfidebondswithreducingreagents.DSTcrosslinkingreagentcanbedissolvedintoanaqueousreaction.