SATAproteinmodifier(N-SuccinimidylS-Acetylthioacetate)isaproteinmodificationreagentusedtoconvertprimaryaminegroupsintoprotectedsulfhydryls(thiol;-SH)forlaterreactionwithsulfhydrylreactivecrosslinkerssuchasSulfo-SMCC,Sulfo-MBS,etc.Thesulfhydrylisre
ADIlymadeavailableforuseinsubsequentreactionsafterexposuretoHydroxylamine.Afterthesimpledeprotectionstepisperformedtocreatethethioacetylatedpeptide,thefreesulfhydrylcontainingpeptidecanthenbeconjugatedtomakeahapten-carrierconjugate,polymer,etc.